Product Code: PA-AICAR-50
CAS Number: 2627-69-2
Molecular Formula: C₉H₁₄N₄O₅
Molecular Weight: 258.23 g/mol
Purity: ≥95% (HPLC)
Form: Lyophilized Powder
 
Product Overview:
 
AICAR (5-Aminoimidazole-4-carboxamide ribonucleoside), also known as Acadesine, is a highly pure research compound designed for advanced scientific studies. As a potent AMP-activated protein kinase (AMPK) activator, AICAR has become an essential tool for researchers investigating cellular metabolism, energy homeostasis, and various physiological processes.nrtimes
 
Key Features:
 
Research Grade Quality: Minimum 95% purity verified by HPLC analysis
Precise Dosage: Each vial contains exactly 50mg of AICAR
Proven Stability: Lyophilized formulation ensures long-term stability
Comprehensive Documentation: Complete analytical data included with every shipment
Fast Shipping: Worldwide delivery with temperature-controlled logistics
 
Research Applications
AICAR has been extensively studied across multiple research domains:

Metabolic Research
Glucose uptake and insulin sensitivity studies pubmed.ncbi.nlm.nih
Lipid metabolism and fatty acid oxidation research
Energy homeostasis investigations
Mitochondrial biogenesis studies
 
Cardiovascular Research
Cardiac protection studies quickanddirtytips
Vascular function research
Atherosclerosis prevention investigations
Endothelial cell studies
 
Anti-Inflammatory Research
 
Inflammatory pathway modulationdrugbank
Cytokine regulation studies
Autoimmune disease research
Oxidative stress investigations
 
Cancer Research
Cell proliferation studiescellsignal+1
Apoptosis research
Tumor metabolism investigations
Chemotherapy enhancement studies
 
Exercise Physiology
Muscle metabolism research hmdb+1
Endurance studies
Fatigue resistance investigations
Athletic performance research
 
Technical Specifications
Parameter
Specification
Appearance
White to off-white lyophilized powder
Purity
≥95% by HPLC
Water Content
≤5%
Solubility
Soluble in water (20 mg/ml), DMSO (40 mg/ml)
pH (1% solution)
5.0 - 7.0
Storage
-20°C, protected from light and moisture

Storage & Handling Instructions
Storage Conditions:
Store at -20°C or lower in original sealed container
Protect from light and moisture
Allow vial to equilibrate to room temperature before opening
Use within 24 months when stored properly
Reconstitution Guidelines:
For aqueous solutions: Use sterile water or appropriate buffer
Recommended concentration: 0.5-2mM for typical applications
Store reconstituted solutions at -20°C in aliquots
Avoid repeated freeze-thaw cycles
 
Mechanism of Action
AICAR functions as an adenosine monophosphate (AMP) analog that effectively activates AMP-activated protein kinase (AMPK). Upon cellular uptake, AICAR is phosphorylated to ZMP (AICAR monophosphate), which mimics AMP and triggers AMPK activation. This activation initiates multiple downstream signaling pathways affecting:wada-ama+1
Energy metabolism regulation
Glucose and lipid homeostasis
Mitochondrial function
Inflammatory responses
Cell survival pathways
 
Quality Assurance:
Every batch of AICAR undergoes rigorous quality control testing:
HPLC Analysis: Confirms purity ≥95%
Mass Spectrometry: Verifies molecular identity
Water Content: Ensures optimal stability
Microbial Testing: Confirms absence of contaminants
Endotoxin Testing: Meets research standards

Documentation Provided
Certificate of Analysis (CoA)
HPLC chromatogram
Mass spectrum data
Storage and handling guidelines
Safety data sheet (SDS)
 
Important Safety Information
⚠️ FOR RESEARCH USE ONLY - NOT FOR HUMAN CONSUMPTION
AICAR is intended exclusively for qualified researchers and laboratory use. This product:
Must be handled by trained personnel only
Requires appropriate safety equipment and ventilation
Should not be used in humans or animals
Is not intended for diagnostic or therapeutic purposes
Ordering Information
Package Size: 50mg per vial
Storage: Ships at ambient temperature, store at -20°C upon receipt
Shelf Life: 24 months when stored properly
Lead Time: Most orders ship within 1-2 business days
Why Choose PeptidesAlpha?
Exceptional Purity: All peptides exceed industry standards
Reliable Supply: Consistent batch-to-batch quality
Expert Support: Technical assistance from peptide specialists
Fast Delivery: Worldwide shipping with tracking
Competitive Pricing: Best value for research-grade peptides