BPC-157, TB-500, KPV & GHK-Cu 80mg (KLOW Blend) – Research Grade Peptide Combination
The KLOW Blend is a synergistic, research-grade peptide formulation specifically designed for laboratory studies on multi-pathway tissue regeneration, recovery modulation, and inflammation resolution. This four-component blend combines the complementary actions of BPC-157, TB-500, KPV, and GHK-Cu to create a comprehensive model for examining systemic healing and cellular repair mechanisms.
Peptide Components & Individual Roles
BPC-157 (Body Protection Compound-157): A pentadecapeptide derived from gastric proteins, BPC-157 is recognized for its potent angiogenic and cytoprotective properties. In research models, it stimulates fibroblast recruitment, enhances blood vessel formation (angiogenesis), and modulates inflammatory cytokine signaling. It operates through multiple pathways including VEGFR2 activation and nitric oxide (NO) signaling, supporting vascular regeneration, tissue remodeling, and cellular protection against oxidative stress.
TB-500 (Thymosin Beta-4 Fragment): A synthetic form of the naturally occurring Thymosin Beta-4, TB-500 is researched for its role in cellular migration, actin polymerization regulation, and angiogenesis. By enhancing endothelial cell movement and promoting actin dynamics, TB-500 supports accelerated structural recovery and wound closure. Its influence on growth factor expression (particularly VEGF upregulation) makes it valuable for examining muscle and cardiovascular tissue repair in experimental systems.
KPV (Lysine-Proline-Valine): A tripeptide fragment derived from alpha-melanocyte stimulating hormone (α-MSH), KPV acts to downregulate inflammatory signaling and promote epithelial barrier integrity. It enters immune and epithelial cells via PepT1 transporters and is explored in research examining gut barrier function, immune modulation, and inflammation resolution.
GHK-Cu (Copper Peptide): A tripeptide complexed with copper ions, GHK-Cu is studied for its broad regenerative properties. Research indicates it upregulates gene expression related to collagen synthesis, glycosaminoglycan production, and antioxidant defense. It modulates metalloproteinase activity, supporting tissue remodeling and protecting against oxidative damage and inflammation.
Synergistic Mechanism & Research Applications
The strength of the KLOW Blend lies in its biological complementarity. Each peptide targets interconnected but distinct pathways in the repair process:
Regeneration & Structural Repair: GHK-Cu and TB-500 promote collagen synthesis, fibroblast activation, and extracellular matrix remodeling, creating a framework for tissue reconstruction.
Vascular Support: BPC-157 and TB-500 drive angiogenesis and microvascular growth, enhancing oxygen and nutrient delivery to damaged tissues.
Inflammation Modulation: KPV and BPC-157 suppress pro-inflammatory cytokines and shift immune response patterns toward resolution, reducing fibrosis and promoting healing.
This multi-system approach makes KLOW ideal for research into systemic regeneration rather than isolated molecular effects.
Research Applications
The KLOW Blend is utilized in studies examining:
Epithelial and muscular tissue repair and recovery
Wound healing and injury rehabilitation models
Inflammatory resolution and immune modulation
Connective tissue and extracellular matrix remodeling
Vascular protection and endothelial function
Multi-pathway regenerative biology
Quality & Specifications
Every batch is synthesized to research-grade specifications with third-party purity verification, stability assessment, and sequence validation. This ensures consistency and reproducibility across experimental studies.
Purity: 99%+ verified
Form: Lyophilized powder
Composition: BPC-157, TB-500, KPV, GHK-Cu
For Research Use Only
The KLOW Blend is intended exclusively for laboratory and in-vitro research applications. Not intended for human consumption or clinical use.