L-Glutathione is a vital antioxidant peptide composed of three amino acids: cysteine, glutamate, and glycine. It is naturally abundant in human tissues but declines with age, affecting multiple biological processes critical for health and longevity. Glutathione acts as a master regulator of oxidative stress, cellular detoxification, and immune function, making it a key molecule in aging, neurodegenerative disease prevention, skin health, and overall wellbeing.
What is L-Glutathione?
L-Glutathione (GSH) is a tripeptide present in almost all body cells, particularly concentrated in the liver, brain, and lungs. It functions primarily as a powerful antioxidant by neutralizing harmful free radicals and reactive oxygen species through redox reactions. This protects DNA, proteins, and cellular structures from oxidative damage, thereby maintaining cellular integrity. Glutathione also supports other antioxidants like vitamins C and E in protecting the body against oxidative stress.
Key Biological Roles
Antioxidant Defense: The sulfur group in the cysteine moiety allows glutathione to scavenge peroxides, nitric oxides, and other reactive toxins, preserving cell function and mitigating damage linked to aging and disease.
Detoxification & Liver Health: Glutathione plays a central role in liver detoxification and is crucial for metabolizing toxins and environmental pollutants.
Support for Immune Function: Glutathione regulates inflammatory responses, enhances immune cell activity, and supports the maintenance of a balanced immune system.
Neuroprotection & Brain Health: Reduced glutathione levels are linked to neurodegenerative disorders like Parkinson’s disease and cognitive decline. Maintaining adequate glutathione helps protect neural tissue from oxidative stress and ferroptosis.
Eye & Skin Health: Glutathione supports retinal cell health and lens clarity, protecting against cataracts and age-related eye degeneration. It also reduces skin aging signs by lowering melanin synthesis and improving elasticity.
Cartilage & Joint Support: By countering oxidative stress, glutathione contributes to the resilience and longevity of cartilage, potentially slowing osteoarthritis progression.
Protein Folding: Glutathione assists in proper protein folding within cells, an essential process for maintaining protein function and cellular health.
Aging and Glutathione
Glutathione levels naturally decrease with age, especially after middle age, resulting in increased oxidative damage and cellular aging. Supplementation is often recommended to restore antioxidant capacity since oral uptake of glutathione itself is poor due to enzymatic breakdown in the digestive tract. Injectable or inhaled forms achieve better bioavailability in research contexts.
Administration and Supplementation
Oral glutathione shows limited bioavailability; therefore, alternative delivery methods like injections or nasal inhalers are preferred in scientific studies for efficiently raising systemic glutathione levels. Research into delivery technologies such as transdermal patches is ongoing.
Complex Role in Cancer
Glutathione’s relationship with cancer is dual-faceted: it protects healthy cells from carcinogens and oxidative stress but can also protect tumor cells during chemotherapy, complicating its role in cancer treatment. However, it can reduce the risk of skin cancer by mitigating UV damage.
Product Details
Content: 600mg L-Glutathione per vial
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.33 g/mol
CAS Number: 170-18-8
Purity: High-purity research grade
Form: Lyophilized powder
Storage: Store in a cool, dry place as per laboratory protocol
Compliance Disclaimer
L-Glutathione 600mg is provided strictly for scientific research and laboratory use only. It is not approved for human or animal consumption and should not be used for medical, therapeutic, or diagnostic purposes. Any bodily administration is prohibited by law.
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