Melanotan 2 (MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH), designed to promote skin tanning without UV exposure. It acts on melanocortin receptors, particularly MC1R and MC4R, influencing melanin production, sexual function, appetite regulation, and behavioral patterns.
What is Melanotan 2?
MT-2 is a synthetic peptide with the sequence Nle-Asp-His-D-Phe-Arg-Trp-Lys and molecular formula C50H69N15O9. It binds melanocortin receptors regulating pigmentation, energy balance, and neurobehavioral functions. Its enhanced blood-brain barrier penetration makes it a potent modulator of central nervous system pathways.
Key Benefits and Research Insights
Skin Pigmentation: MT-2 stimulates melanocytes via MC1R, increasing melanin synthesis and promoting a natural tan, offering an alternative to UV tanning.
Sexual Function: Activation of MC4R enhances sexual arousal and erectile function, with potential applications in treating hypoactive sexual desire and erectile dysfunction.
Autism Model Reversal: Research demonstrates MT-2’s ability to reverse autism-like behaviors in mouse models by modulating oxytocin receptor expression and improving social interactions.
Appetite and Weight Regulation: MT-2 reduces hunger, alters food preferences away from high-fat foods, and mimics leptin activity by suppressing glucagon, suggesting utility in metabolic disorder research.
Diabetes and Glucose Metabolism: MT-2 influences pancreatic hormone secretion, enhancing glucose uptake and reducing ketone body production, highlighting potential diabetes research applications.
Addiction and Impulse Control: Animal studies show MT-2 decreases alcohol consumption and impulsivity, especially when combined with addiction medications, through modulation of brain reward pathways.
Neurological Effects: Beyond melanoma and metabolism, MT-2 exhibits neuroprotective and behavioral-modulating effects, supporting studies in mood regulation and cognitive function.
Specifications
Content: 10mg Melanotan 2 peptide per vial
Sequence: Nle-Asp-His-D-Phe-Arg-Trp-Lys
Molecular Formula: C50H69N15O9
CAS Number: 121062-08-6
Purity: >98%, research-grade lyophilized powder
Storage: Store in a cool, dry place, protected from light as per lab guidelines
Research Usage and Safety
Melanotan 2 is intended solely for in-vitro and laboratory research. It is not approved for human or veterinary use and must not be administered to individuals or animals. Research studies document minimal to moderate side effects, and MT-2 shows excellent bioavailability upon subcutaneous administration in experiments.
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Melanotan 2 (MT2) 10mg
- Typical dosages can range, but commonly it’s 2mg per vial, which can be reconstituted with sterile water.
- The peptide is typically administered via subcutaneous injection.
- The dosing regimen often involves one injection per week, as it has a prolonged half-life (due to the DAC component).
- As with any peptide, there could be risks, such as injection site reactions, water retention, or possible changes in insulin sensitivity.
- It’s important to monitor health regularly and consult with a healthcare provider, especially if using for long-term purposes.
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