Pancragen is a naturally occurring tetrapeptide bioregulator with targeted effects on the pancreas. It supports pancreatic endocrine function, helps regulate blood sugar levels, modulates melatonin expression, and may reduce the incidence and severity of metabolic syndrome. Pancragen is researched for its potential in treating diabetes and mitigating age-related metabolic dysfunction, making it a promising anti-aging peptide for pancreatic health.
What is Pancragen?
Pancragen has the amino acid sequence Lys-Glu-Asp-Trp (KEDW) and influences cellular differentiation factors critical to pancreatic tissue health, including acinar and islet of Langerhans cells responsible for insulin and glucagon production. By restoring gene expression patterns and improving cellular differentiation, Pancragen helps rejuvenate pancreatic function, thereby reversing features associated with aging.
Key Research Highlights
Pancreatic Cell Function and Aging: Pancragen promotes the expression of differentiation, proliferation, and survival markers in pancreatic cells, supporting renewed functionality typical of youthful tissue.
Metabolic Syndrome Regulation: By normalizing insulin secretion and modulating melatonin levels, Pancragen may alleviate symptoms associated with metabolic syndrome, including insulin resistance and glucose intolerance.
Diabetes Management: Studies in aged rhesus monkeys have shown Pancragen's ability to normalize blood glucose, insulin, and C-peptide levels more physiologically than some diabetes drugs, with effects lasting several weeks after administration.
Vascular Protection: Pancragen supports endothelial cell function in capillaries vulnerable to damage in diabetes, potentially reducing complications such as cardiovascular disease and erectile dysfunction linked to microvascular damage.
Mechanism of Action: Research suggests Pancragen exerts effects through epigenetic regulation, altering DNA methylation and gene expression to improve pancreatic cell activity and metabolic health.
Molecular and Product Details
Peptide Sequence: Lys-Glu-Asp-Trp (KEDW)
Molecular Formula: C26H36N6O9
Molecular Weight: 576.25 g/mol
Synonyms: SCHEMBL5491754
Purity: High-purity research grade peptide
Form: Lyophilized powder suitable for laboratory use
Storage: Store in a cool, dry place per laboratory guidelines
Research Applications
Pancragen is a candidate for research into anti-aging therapies targeting pancreatic function, diabetes management, and metabolic syndrome. Its regulatory effects on insulin and melatonin pathways, along with vascular support, make it of interest for advancing treatments of age-related metabolic diseases.
Compliance Disclaimer
Pancragen 20mg from PeptidesAlpha is strictly for in-vitro research purposes only. It is not approved for human or veterinary use, nor for medical treatment or diagnosis. Usage is restricted to controlled research environments in compliance with regulations.
PeptidesAlpha offers high-quality Pancragen peptides to empower advanced diabetes, metabolic, and pancreatic research with guaranteed purity and efficacy.