Product: Sermorelin (GHRH 1-29) - 2mg Research Grade
Unlock the powerful potential of growth hormone-releasing hormone research with our premium Sermorelin peptide. As a synthetic 29-amino acid analogue of naturally occurring GHRH, Sermorelin represents the shortest fully functional fragment capable of stimulating natural growth hormone secretion, making it an invaluable tool for advanced endocrine and metabolic research.
Research Applications & Mechanisms:
Sermorelin operates by binding to growth hormone-releasing hormone receptors in the anterior pituitary gland, triggering the natural, pulsatile release of endogenous growth hormone. Unlike direct hormone administration, Sermorelin works upstream in the regulatory pathway, preserving physiological feedback mechanisms through somatostatin regulation. This makes it essential for research into:
Cardiovascular Health Studies: Investigation of cardiac remodeling reduction and myocardial protection following ischemic events
Neurological Research: Exploring GABA receptor activation for seizure suppression and epilepsy management
Sleep Science Applications: Research into orexin pathway regulation and sleep cycle optimization
Metabolic Research: Understanding natural growth hormone dynamics and IGF-1 pathway activation
Anti-Aging Studies: Investigation of age-related hormone decline and physiological restoration
Bone Density Research: Exploring growth hormone effects on bone mineralization and osteoporosis prevention
Advanced Research Benefits:
Our Sermorelin peptide demonstrates exceptional research versatility through its unique physiological approach. Studies indicate that Sermorelin stimulates pituitary gene transcription of growth hormone messenger RNA, increasing pituitary reserve while preserving the growth hormone neuroendocrine axis. This natural stimulation approach avoids tachyphylaxis and provides sustained research reliability.
The peptide's ability to promote episodic, rather than constant, growth hormone release makes it ideal for studying natural hormone dynamics. Research applications include cardiac tissue repair through reduced cell death in cardiomyocytes, increased extracellular matrix production, enhanced angiogenesis, and reduced inflammatory responses.
In neurological research, Sermorelin's activation of GABA receptors offers unique opportunities for seizure activity studies, while its influence on orexin secretion provides insights into sleep regulation mechanisms and circadian rhythm research.
Quality Specifications:
Purity: >98% by analytical HPLC
Molecular Weight: 3357.9 g/mol
Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Appearance: White to off-white lyophilized powder
Storage: -20°C for optimal long-term stability
Solubility: Reconstitute in sterile water or appropriate buffer solutions
Half-life: 11-12 minutes (allowing for precise research protocols)
Research-Grade Excellence:
Each batch undergoes comprehensive analytical characterization including mass spectrometry verification, amino acid sequence confirmation, and purity assessment by reversed-phase HPLC. Our quality control processes ensure consistent biological activity and structural integrity for reliable research outcomes.
The peptide demonstrates excellent stability when stored properly and maintains consistent receptor binding affinity across multiple freeze-thaw cycles, making it ideal for extended research protocols.
Innovative Research Opportunities:
Sermorelin's multi-system effects make it invaluable for investigating:
Natural growth hormone regulation pathways
Pituitary gland function and hormone axis preservation
Age-related endocrine system changes
Cardiac protection and tissue repair mechanisms
Sleep architecture and circadian biology
Metabolic homeostasis and body composition regulation
Bone metabolism and mineralization processes
Cognitive function and neuroplasticity research
Physiological Research Advantages:
Unlike exogenous growth hormone administration, Sermorelin research allows investigation of natural regulatory mechanisms. The peptide's effects are modulated by physiological feedback involving somatostatin, preventing supraphysiological responses and maintaining research relevance to natural biological processes.
Sermorelin's unique property of avoiding receptor downregulation makes it particularly valuable for long-term studies, as the body actually increases GHRH receptor production rather than decreasing sensitivity over time.
Professional Research Support:
Ideal for pharmaceutical research, academic endocrine studies, and biotechnology applications. Our Sermorelin peptide supports cutting-edge investigations into growth hormone biology, from traditional pediatric growth studies to innovative applications in cardiovascular protection, neurological disorders, and age-related physiological changes.
Technical Specifications:
pH Range: 6.0-8.0 when reconstituted
Endotoxin Level: <1.0 EU/mg
Solubility: >2mg/ml in physiological saline
Storage Buffer: Lyophilized from acetate buffer
Important Research Notice:
This product is intended for research use only. Not for human consumption, therapeutic use, or diagnostic applications. Proper laboratory safety protocols and institutional oversight should be maintained when conducting research with this material.
Advance your growth hormone and endocrine research with confidence using our premium Sermorelin peptide - where scientific precision meets research innovation.