Molecular Formula: C₁₇H₂₉N₅O₉
Molecular Weight: 447.2 g/mol
Sequence: Lys-Glu-Asp-Gly (KEDG)
Purity: >99%
Vial Size: 20mg
Storage: -20°C, protect from light
Product Overview
Testagen represents cutting-edge bioregulatory peptide technology designed for comprehensive endocrine and anti-aging research applications. This Khavinson-developed tetrapeptide demonstrates unique ability to traverse cellular and nuclear membranes, directly interacting with DNA to regulate gene expression and protein synthesis. Unlike traditional hormone replacement approaches, Testagen works upstream by resetting pituitary function to more youthful states, naturally optimizing hormonal cascades.
Revolutionary Bioregulator Mechanism
Testagen functions as a specialized pituitary-thyroid axis modulator, stimulating anterior pituitary gland to enhance thyroid-stimulating hormone release while subsequently increasing T3 and T4 thyroid hormone production. This epigenetic regulation occurs even without hypophyseal support, demonstrating direct protein expression alteration in pituitary tissue. The peptide's unique chromatin interaction capabilities enable targeted gene activation for hormonal optimization and cellular regeneration.
Primary Research Applications
Testosterone Regulation Studies
Research demonstrates Testagen's ability to normalize testosterone production through pituitary-gonadal axis optimization. Clinical investigations show improvements in uroflowmetry indicators, reduced inflammatory markers, and elevated total testosterone levels. Applications include age-related hypogonadism research, reproductive function studies, and male vitality optimization.
Thyroid Function Research
Studies in hypophysectomized models reveal significant thyroid restoration capabilities. Testagen administration resulted in 23% body weight increase, thyroid gland weight normalization, and morphological improvements including reduced follicular area and prevented epithelium flattening. Research applications encompass hypothyroidism studies and metabolic regulation investigations.
Anti-Aging Research
Comprehensive studies demonstrate Testagen's geroprotective properties through stem cell differentiation enhancement and immune system modulation. Research shows improved cellular regeneration, reduced chromatin condensation effects, and enhanced immune surveillance capabilities, positioning it as valuable tool for longevity mechanism studies.
Immune System Enhancement
Dr. Khavinson's research reveals Testagen's capacity to promote stem cell differentiation into immune system cells, enhancing immune function particularly in elderly populations. Applications include immunosenescence research, autoimmune condition studies, and cellular differentiation investigations.
Hemostasis Research
Preliminary studies suggest Testagen's beneficial effects on blood clotting mechanisms through pituitary regulation. Research applications include coagulation disorder studies and vascular health investigations linked to endocrine function.
Mechanism of Action
Pituitary Activation: Direct stimulation of TSH release and hormonal cascade initiation
Epigenetic Regulation: DNA interaction and chromatin modification for gene expression control
Testosterone Optimization: Natural stimulation of endogenous hormone synthesis pathways
Thyroid Enhancement: Morphological and functional restoration of thyroid tissue
Immune Modulation: Stem cell differentiation promotion and immune surveillance enhancement
Anti-Aging Effects: Cellular regeneration and senescence prevention mechanisms
Research Advantages
Nuclear Penetration: Crosses cell and nuclear membranes for direct DNA interaction
Tissue-Specific Action: Concentrated effects on pituitary and thyroid systems
Natural Optimization: Stimulates endogenous hormone production rather than replacement
Multi-System Benefits: Endocrine, immune, and vascular applications
Clinical Foundation: Extensive research validation by leading peptide scientists
Minimal Side Effects: Well-tolerated bioregulatory approach
Anti-Aging Properties: Proven geroprotective and cellular regeneration capabilities
Quality Specifications
Every Testagen batch undergoes comprehensive quality control:
HPLC-MS purity analysis confirming >99% purity
Amino acid sequence verification (Lys-Glu-Asp-Gly)
Molecular weight confirmation at 447.2 g/mol
Endotoxin testing (<0.1 EU/mg)
DNA interaction capability validation
Bioactivity assays using pituitary cell lines
Certificate of Analysis provided with shipment
Storage & Reconstitution
Store lyophilized powder at -20°C in sealed vials. Protect from light and humidity. Reconstitute with bacteriostatic water immediately before use. Once reconstituted, use within 24 hours or store at -80°C for short-term applications. Avoid repeated freeze-thaw cycles to maintain DNA binding affinity and biological activity.
Research Protocol Applications
Testosterone optimization and male reproductive health studies
Thyroid function restoration and metabolic research
Anti-aging mechanism investigations and longevity studies
Immune system enhancement and stem cell differentiation research
Pituitary-thyroid axis regulation studies
Epigenetic mechanism and gene expression research
Hormonal cascade optimization investigations
Cellular regeneration and senescence prevention studies
Clinical Translation Potential
Testagen research benefits from four decades of investigation by Professor Vladimir Khavinson and extensive validation in bioregulatory peptide applications. The peptide's proven mechanisms in pituitary-thyroid optimization, testosterone enhancement, and immune system modulation provide robust foundation for investigating novel therapeutic applications in endocrine disorders, age-related decline, and regenerative medicine.
Research Use Only: Not for human or veterinary therapeutic applications. Handle according to laboratory safety protocols and institutional research guidelines.
Testagen 20mg
Typical research protocols: 1-2mg daily for cellular studies
Reconstitute with sterile bacteriostatic water
Administration methods: Subcutaneous or cell culture applications
Monitor for endocrine system responses and cellular differentiation markers
Regular hormone level monitoring recommended during extended protocols
Follow institutional guidelines for bioregulatory peptide handling procedures