Molecular Formula: C₉H₁₄N₂O₇
Molecular Weight: 262.20 g/mol
Sequence: Glu-Asp (ED)
Purity: >99%
Vial Size: 20mg
Storage: -20°C, protect from light
Product Overview
Vesilute represents advanced bioregulatory peptide technology designed for comprehensive urogenital, vascular, and cellular aging research applications. This Khavinson-developed dipeptide demonstrates exceptional ability to regulate urinary tract function, enhance prostate health, and promote cellular regeneration through direct interaction with chromatin structures and smooth muscle regulation. Unlike traditional urological interventions, Vesilute works epigenetically by modulating gene expression and improving microcirculation to restore optimal organ function.
Revolutionary Urogenital Mechanism
Vesilute functions as a specialized bioregulator through direct interaction with heterochromatin regions in cell nuclei, promoting chromatin decondensation to reactivate genes silenced during cellular aging. The peptide demonstrates anti-aggregation effects on smooth muscle by interfering with glycogen phosphorylase activation, preventing glycogen breakdown and inducing muscle relaxation. This dual mechanism enhances microcirculation while reducing inflammatory processes, particularly beneficial for tissues with abundant smooth muscle such as the urinary tract and vascular system.
Primary Research Applications
Prostate Health Research
Clinical studies demonstrate significant improvements in benign prostatic hyperplasia symptoms through enhanced microcirculation and reduced cell proliferation. Research shows decreased prostate fibrosis, improved urinary flow rates, and reduced inflammatory markers. Studies reveal 29% increase in sperm production and 14% improvement in sperm viability following prostatitis treatment, positioning it as valuable tool for investigating male reproductive health and fertility enhancement mechanisms.
Bladder Function Studies
Research demonstrates enhanced bladder function particularly in elderly populations, with improvements in chronic cystitis symptoms and urinary dysfunction. Studies show reduced detrusor overactivity, improved bladder capacity, and normalized micturition patterns. Clinical applications include investigating overactive bladder mechanisms, urinary incontinence pathways, and age-related urological changes through smooth muscle regulation research.
Vascular Health Research
Studies reveal significant effects on smooth muscle aggregation in blood vessels, leading to vessel relaxation, reduced blood pressure, and improved nutrient delivery to organs. Research demonstrates enhanced microvascular circulation with beneficial effects on cardiovascular health, kidney function, and overall vascular integrity. Applications encompass hypertension research, microcirculation studies, and cardiovascular aging investigations.
Male Fertility Enhancement
Comprehensive research shows substantial improvements in spermatogenesis through enhanced prostate microcirculation and reduced inflammatory processes. Studies demonstrate increased sperm count, motility, and viability while decreasing abnormal sperm morphology. Research applications include investigating infertility mechanisms, reproductive aging, and therapeutic approaches for male reproductive dysfunction.
Anti-Aging & Gene Expression Research
Studies demonstrate Vesilute's ability to activate heterochromatinized chromosome regions in aging cells, potentially reactivating silenced genes and promoting protein synthesis. Research shows chromatin decondensation effects that may counteract cellular aging processes. Applications include investigating epigenetic aging mechanisms, gene reactivation therapies, and longevity enhancement strategies.
Mechanism of Action
Chromatin Regulation: Direct interaction with heterochromatin promoting gene reactivation in aging cells
Smooth Muscle Relaxation: Anti-aggregation effects preventing glycogen breakdown and inducing muscle relaxation
Microcirculation Enhancement: Improved blood flow reducing inflammation and promoting tissue repair
Anti-Proliferative Effects: Reduced abnormal cell proliferation particularly in prostate tissues
Umami Receptor Activation: Natural flavor enhancement suggesting evolutionary importance in biochemical processes
Orally Active: Demonstrated bioavailability through oral administration routes
Research Advantages
Multi-System Effects: Simultaneous urogenital, vascular, and anti-aging applications
Epigenetic Action: Direct chromatin interaction providing targeted gene expression regulation
Clinical Foundation: Extensive validation in urological and fertility applications
Oral Bioavailability: Effective through multiple administration routes including oral delivery
Minimal Side Effects: Well-tolerated bioregulatory approach with established safety profile
Evolutionary Significance: Natural umami flavor suggests important biological functions
Age-Specific Benefits: Enhanced efficacy in elderly populations with age-related dysfunction
Quality Specifications
Every Vesilute batch undergoes comprehensive quality control:
HPLC-MS purity analysis confirming >99% purity
Dipeptide sequence verification (Glu-Asp)
Molecular weight confirmation at 262.20 g/mol
CAS number validation (3918-84-1)
PubChem CID verification (99716)
Endotoxin testing (<0.1 EU/mg)
Certificate of Analysis provided with shipment
Storage & Reconstitution
Store lyophilized powder at -20°C in sealed vials. Protect from light and humidity. Reconstitute with sterile bacteriostatic water immediately before use. Once reconstituted, use within 24 hours or store at -80°C for short-term applications. Avoid repeated freeze-thaw cycles to maintain chromatin-binding affinity and smooth muscle regulatory potency.
Research Protocol Applications
Prostate health and benign prostatic hyperplasia mechanism studies
Bladder function and overactive bladder syndrome research
Male fertility and spermatogenesis enhancement investigations
Vascular health and microcirculation improvement studies
Anti-aging and gene expression reactivation research
Smooth muscle function and relaxation mechanism studies
Chronic cystitis and urinary tract dysfunction investigations
Epigenetic regulation and chromatin modification research
Clinical Translation Potential
Vesilute benefits from decades of investigation by Professor Vladimir Khavinson with extensive validation in urological and reproductive health applications. The peptide's proven mechanisms in prostate protection, fertility enhancement, and vascular health provide robust foundation for investigating novel therapeutic applications in urogenital disorders, male reproductive medicine, and age-related conditions.
Research Use Only: Not for human or veterinary therapeutic applications. Handle according to laboratory safety protocols and institutional research guidelines.